Interactor 1: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3
Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.99 | 1.00 | 0.996 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12473110, 25636800, 26347139, 26456228, 26407194, 26221961, 23986588, 27956528, 30770245, 24016850, 31308089, 32476569, 18309294, 34084167, 35103914, 19454348, 19893624, 22114345, 22588174, 21782231 and 32 others
more... |
Identification Methods | affinity chromatography technology, protein complementation assay, pull down, comigration in non denaturing gel electrophoresis, anti tag coimmunoprecipitation, polymerization, blue native page, tandem affinity purification, cosedimentation in solution, molecular sieving and 1 others
more... |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | IRF~IRF, IRF-3~IRF-3 |
Common GO terms | GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001216 - DNA-binding transcription activator activity GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific and 42 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024