HitPredict

Interactor 1: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Interactor 2: IFNL1 (Q8IU54)
Interferon lambda-1 (IFN-lambda-1) (Cytokine Zcyto21) (Interleukin-29) (IL-29)
Gene: IFNL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17785777
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response GO:0051607 - defense response to virus GO:0098586 - cellular response to virus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 200
+	Hs
		1056436 IRF3_HUMAN (1-427): 0: 604: 100.00		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		971740 IRF8_HUMAN (7-387): 6.94e-148: 428: 27.32		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		971741 IRF8_HUMAN (7-387): 6.94e-148: 428: 27.32		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		1215834 IRF7_HUMAN (4-383): 1.71e-105: 323: 26.03		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		1224458 IRF7_HUMAN (4-383): 1.71e-105: 323: 26.03		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94
+	Hs
		501063 IRF1_HUMAN (1-189): 8.3e-49: 170: 24.23		IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00
+	Hs
		501067 IRF1_HUMAN (1-189): 8.3e-49: 170: 24.23		IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94