HitPredict

Interactor 1: TRIPC (Q14669)
E3 ubiquitin-protein ligase TRIP12 (EC 2.3.2.26) (E3 ubiquitin-protein ligase for Arf) (ULF) (HECT-type E3 ubiquitin transferase TRIP12) (Thyroid receptor-interacting protein 12) (TR-interacting protein 12) (TRIP-12)
Gene: TRIP12

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27634302
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1992 Hs			1 746
+	Hs
		125489 WWP2_HUMAN (1053-1990): 0: 603: 18.31		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1080322 WWP1_HUMAN (1038-1990): 0: 580: 16.88		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1080361 SMUF2_HUMAN (1373-1989): 2.4e-168: 535: 19.18		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		808137 NEDD4_HUMAN (814-1990): 2.08e-159: 528: 13.49		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		131444 IMA4_HUMAN (363-864): 7.19e-155: 489: 13.73		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		134905 IMA3_HUMAN (365-866): 1.41e-154: 488: 13.33		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		1080081 HUWE1_HUMAN (1616-1992): 2.18e-25: 118: 28.72		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		975337 HECW2_HUMAN (924-1991): 0: 626: 14.87		KMT2A_HUMAN (606-733): 6.89e-19: 94.4: 39.54
+	Hs
		331902 HECD1_HUMAN (437-1230): 6.18e-77: 287: 15.52		NSD2_HUMAN (275-729): 1.99e-91: 314: 16.03