HitPredict

Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: CYTSA (Q69YQ0)
Cytospin-A (Renal carcinoma antigen NY-REN-22) (Sperm antigen with calponin homology and coiled-coil domains 1-like) (SPECC1-like protein)
Gene: SPECC1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29656893
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2089 Hs			1 1117
+	Hs
		211525 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Ce
		110503 O17084_CAEEL (66-1982): 4.35e-51: 202: 9.26		H2L2C8_CAEEL (1009-1116): 1.45e-49: 192: 43.12
+	Ce
		184367 O17084_CAEEL (66-1982): 4.35e-51: 202: 9.26		Q23158_CAEEL (1009-1116): 1.02e-46: 184: 40.37
+	Hs
		502905 KI67_HUMAN (38-1868): 2.43e-65: 249: 11.53		MYH3_HUMAN (372-1035): 6.82e-24: 111: 10.16
+	Hs
		993278 TITIN_HUMAN (175-1895): 2.81e-32: 141: 8.72		ACTN3_HUMAN (1009-1115): 7.86e-51: 196: 40.74
+	Hs
		521586 TITIN_HUMAN (175-1895): 2.81e-32: 141: 8.72		ACTN1_HUMAN (1009-1116): 3.96e-50: 194: 42.20
+	Hs
		725681 TITIN_HUMAN (175-1895): 2.81e-32: 141: 8.72		ACTN2_HUMAN (1009-1115): 3.7e-48: 188: 41.67
+	Hs
		211629 TITIN_HUMAN (175-1895): 2.81e-32: 141: 8.72		ACTN4_HUMAN (1009-1116): 6.66e-48: 187: 41.28
+	Dm
		574825 TITIN_DROME (757-1667): 2e-11: 72: 12.37		ACTN_DROME (1009-1116): 2.32e-50: 195: 37.62
+	Hs
		724782 ANK2_HUMAN (608-1849): 1.3e-11: 72.7: 10.40		MYH9_HUMAN (206-1087): 3.64e-34: 144: 11.77
+	Hs
		725139 ANK2_HUMAN (608-1849): 1.3e-11: 72.7: 10.40		MYH10_HUMAN (213-1075): 1.21e-33: 143: 10.62
+	Dm
		404245 TITIN_DROME (757-1667): 2e-11: 72: 12.37		MYSA_DROME (9-775): 1.21e-27: 123: 9.63