Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: FACD2 (Q9BXW9)
Fanconi anemia group D2 protein (Protein FACD2)
Gene: FANCD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 31180492, 29656893, 12607005
Identification Methods affinity chromatography technology, proximity labelling technology, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016604 - nuclear body
GO:0031573 - mitotic intra-S DNA damage checkpoint signaling
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 2089
Hs

1 1451
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024