HitPredict

Interactor 1: KCTD2 (Q14681)
BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerization domain-containing protein 2)
Gene: KCTD2

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34315543
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 263 Hs			1 541
+	Hs
		1296929 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1252628 SHKB1_HUMAN (57-183): 2.75e-35: 135: 40.95		SNX27_HUMAN (1-541): 0: 625: 100.00
+	Hs
		1057222 KCTD2_HUMAN (1-263): 5.89e-84: 253: 100.00		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		153919 KCTD2_HUMAN (1-263): 5.89e-84: 253: 100.00		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Hs
		1235392 KCD17_HUMAN (72-254): 1.23e-58: 190: 72.13		NEB1_HUMAN (40-375): 2.86e-39: 155: 14.43
+	Hs
		1057225 KCTD2_HUMAN (1-263): 5.89e-84: 253: 100.00		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		67909 KCTD2_HUMAN (1-263): 5.89e-84: 253: 100.00		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23
+	Hs
		1075465 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		153954 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Hs
		1132926 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		67923 KCTD5_HUMAN (66-263): 2.12e-73: 225: 80.81		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23
+	Hs
		1075429 KCD17_HUMAN (72-254): 1.23e-58: 190: 72.13		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		1075459 BACD3_HUMAN (37-253): 1.35e-55: 182: 24.77		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		1132909 KCD17_HUMAN (72-254): 1.23e-58: 190: 72.13		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		67915 KCD17_HUMAN (72-254): 1.23e-58: 190: 72.13		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23
+	Mm
		761860 BACD1_MOUSE (34-252): 9.17e-58: 188: 21.17		ZO1_MOUSE (12-254): 1.04e-10: 66.8: 13.10
+	Hs
		1075432 SHKB1_HUMAN (57-183): 2.75e-35: 135: 40.95		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		153935 SHKB1_HUMAN (57-183): 2.75e-35: 135: 40.95		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Hs
		1132910 SHKB1_HUMAN (57-183): 2.75e-35: 135: 40.95		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		67916 SHKB1_HUMAN (57-183): 2.75e-35: 135: 40.95		PDZ1P_HUMAN (38-282): 1.35e-15: 80.7: 14.23