HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: Q58EY0 (Q58EY0)
RAR related orphan receptor B isoform 1 (RAR-related orphan receptor B) (cDNA, FLJ93970, Homo sapiens RAR-related orphan receptor B (RORB), mRNA)
Gene: RORB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15604093
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2063 Hs			1 459
+	Hs
		846412 NCOA6_HUMAN (1-2063): 0: 746: 100.00		RORG_HUMAN (2-454): 9.76e-106: 325: 46.25
+	Hs
		874381 NCOA6_HUMAN (1-2063): 0: 746: 100.00		NR1H2_HUMAN (7-453): 2.28e-87: 276: 19.91
+	Hs
		509950 NCOA6_HUMAN (1-2063): 0: 746: 100.00		VDR_HUMAN (3-453): 6.64e-82: 261: 21.44
+	Hs
		265866 NCOA6_HUMAN (1-2063): 0: 746: 100.00		NR1I2_HUMAN (8-452): 8.17e-81: 258: 22.72
+	Hs
		740524 NCOA6_HUMAN (1-2063): 0: 746: 100.00		PPARG_HUMAN (8-128): 1.04e-45: 167: 46.34
+	Hs
		487970 NCOA6_HUMAN (1-2063): 0: 746: 100.00		RARA_HUMAN (9-84): 3.92e-43: 159: 61.84
+	Hs
		587169 NCOA6_HUMAN (1-2063): 0: 746: 100.00		RXRA_HUMAN (10-91): 4.41e-28: 117: 57.32
+	Hs
		130339 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		NR5A2_HUMAN (3-446): 6.54e-99: 308: 23.98
+	Hs
		592827 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		NR1D1_HUMAN (9-432): 1.47e-92: 294: 28.27
+	Hs
		874405 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		NR1H2_HUMAN (7-453): 2.28e-87: 276: 19.91
+	Hs
		509999 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		VDR_HUMAN (3-453): 6.64e-82: 261: 21.44
+	Hs
		265885 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		NR1I2_HUMAN (8-452): 8.17e-81: 258: 22.72
+	Hs
		554279 MUC1_HUMAN (159-883): 4.81e-23: 110: 10.47		PPARG_HUMAN (8-128): 1.04e-45: 167: 46.34
+	Hs
		500380 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		RARB_HUMAN (9-138): 6.04e-46: 167: 42.31
+	Hs
		740633 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		PPARG_HUMAN (8-128): 1.04e-45: 167: 46.34
+	Hs
		530817 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		RARG_HUMAN (9-84): 1.22e-44: 163: 63.16
+	Hs
		488042 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		RARA_HUMAN (9-84): 3.92e-43: 159: 61.84
+	Hs
		587211 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		RXRA_HUMAN (10-91): 4.41e-28: 117: 57.32
+	Hs
		818890 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		RXRG_HUMAN (10-96): 2.96e-27: 115: 54.02
+	Hs
		975486 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		PPARD_HUMAN (244-450): 1.28e-15: 80.5: 26.07