HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	12482968
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 2063 Hs			1 136
+	Hs
		820879 PRC2A_HUMAN (208-2062): 5.88e-16: 86.8: 7.66		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		934763 MDC1_HUMAN (157-945): 1.46e-12: 75.8: 11.15		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952338 MDC1_HUMAN (157-945): 1.46e-12: 75.8: 11.15		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		935324 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		935004 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952670 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		1086228 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Hs
		1174600 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Hs
		935150 MINT_HUMAN (1100-2062): 1.16e-09: 66.2: 9.24		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952479 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		935378 SRRM2_HUMAN (1328-2061): 5.87e-09: 63.7: 10.47		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Hs
		952573 MINT_HUMAN (1100-2062): 1.16e-09: 66.2: 9.24		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		1174692 SRRM2_HUMAN (1328-2061): 5.87e-09: 63.7: 10.47		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Mm
		101827 F8WI37_MOUSE (1016-1986): 8.56e-09: 63.2: 13.97		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Hs
		828410 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00