HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28813667
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2063 Hs			1 1962
+	Hs
		820978 PRC2A_HUMAN (208-2062): 5.88e-16: 86.8: 7.66		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Mm
		1207212 NCOA6_MOUSE (1-2063): 0: 728: 90.67		KMT2C_MOUSE (978-1884): 1.32e-29: 132: 11.29
+	Hs
		1057781 NCOA6_HUMAN (1-2063): 0: 746: 100.00		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		1057773 NCOA6_HUMAN (1-2063): 0: 746: 100.00		KMT2C_HUMAN (1071-1765): 1.31e-13: 79.4: 10.54
+	Hs
		998713 NCOA6_HUMAN (1-2063): 0: 746: 100.00		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		821090 PRC2A_HUMAN (208-2062): 5.88e-16: 86.8: 7.66		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		821046 PRC2A_HUMAN (208-2062): 5.88e-16: 86.8: 7.66		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Dm
		1370333 Q9VLS7_DROME (1052-2062): 6.68e-21: 102: 9.01		Q9VXR3_DROME (1321-1891): 6.42e-39: 162: 13.36
+	Hs
		1302939 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		MINT_HUMAN (30-1804): 8.51e-28: 125: 8.46
+	Hs
		1329244 TARA_HUMAN (168-1726): 1.14e-25: 118: 9.69		TARA_HUMAN (38-1689): 5.35e-20: 100: 8.89
+	Hs
		1270850 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Hs
		554259 MUC1_HUMAN (159-883): 4.81e-23: 110: 10.47		MUC1_HUMAN (845-1740): 1.98e-15: 84.9: 11.69
+	Hs
		311825 TACC2_HUMAN (134-1918): 4.74e-16: 87.2: 8.66		CBP_HUMAN (735-1745): 8.61e-21: 102: 9.54
+	Mm
		57185 SMCA4_MOUSE (351-700): 1.27e-23: 112: 16.81		CHD7_MOUSE (1210-1786): 2.83e-12: 74.8: 10.31
+	Hs
		554303 MUC1_HUMAN (159-883): 4.81e-23: 110: 10.47		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		999262 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		311805 TACC2_HUMAN (134-1918): 4.74e-16: 87.2: 8.66		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Mm
		1351630 PCLO_MOUSE (111-2043): 7.56e-15: 83.3: 8.34		PCLO_MOUSE (19-1290): 1.41e-09: 66: 10.73
+	Hs
		999216 BSN_HUMAN (160-1946): 1.34e-14: 82.5: 8.40		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		998710 MDC1_HUMAN (157-945): 1.46e-12: 75.8: 11.15		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05