HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: SP7 (Q8TDD2)
Transcription factor Sp7 (Zinc finger protein osterix)
Gene: SP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2063 Hs			1 431
+	Hs
		131733 BCL9_HUMAN (109-1440): 4.55e-36: 152: 9.92		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		1254974 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		1244273 ARI1B_HUMAN (582-2022): 5.83e-14: 80.2: 10.54		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		1254942 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		1243829 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		SP7_HUMAN (1-431): 1.9e-116: 348: 100.00
+	Hs
		131750 BCL9_HUMAN (109-1440): 4.55e-36: 152: 9.92		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		435196 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		SP1_HUMAN (195-410): 2.85e-40: 155: 46.30
+	Hs
		821027 PRC2A_HUMAN (208-2062): 5.88e-16: 86.8: 7.66		KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67
+	Hs
		1355815 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		317047 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		821074 PRC2A_HUMAN (208-2062): 5.88e-16: 86.8: 7.66		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		1315379 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67
+	Hs
		316821 PRC2A_HUMAN (208-2062): 5.88e-16: 86.8: 7.66		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		1350247 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		KLF12_HUMAN (289-376): 4.7e-24: 105: 56.82
+	Hs
		317017 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		1243850 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		KLF15_HUMAN (293-379): 6.68e-24: 104: 59.77
+	Hs
		1056958 MDC1_HUMAN (157-945): 1.46e-12: 75.8: 11.15		ZN251_HUMAN (320-430): 1.13e-19: 93.5: 21.43
+	Hs
		316970 MINT_HUMAN (1100-2062): 1.16e-09: 66.2: 9.24		KLF8_HUMAN (282-376): 5.53e-24: 103: 53.68
+	Hs
		997548 SRRM2_HUMAN (1328-2061): 5.87e-09: 63.7: 10.47		ZN543_HUMAN (33-137): 2.85e-13: 73.5: 10.38
+	Dm
		81161 LINT_DROME (274-1553): 7.56e-09: 63.5: 8.86		Q8MLQ3_DROME (321-376): 3.37e-12: 69.3: 58.93