HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: FEV (Q99581)
Protein FEV (Fifth Ewing variant protein) (PC12 ETS domain-containing transcription factor 1) (PC12 ETS factor 1) (Pet-1)
Gene: FEV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2063 Hs			1 238
+	Hs
		507423 NCOA6_HUMAN (1-2063): 0: 746: 100.00		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		131739 BCL9_HUMAN (109-1440): 4.55e-36: 152: 9.92		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		1304732 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		131687 BCL9_HUMAN (109-1440): 4.55e-36: 152: 9.92		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		1244292 ARI1B_HUMAN (582-2022): 5.83e-14: 80.2: 10.54		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		1304713 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		1243834 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		131699 BCL9_HUMAN (109-1440): 4.55e-36: 152: 9.92		ETV4_HUMAN (36-186): 3.64e-46: 161: 39.74
+	Hs
		507534 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		507469 ARI1B_HUMAN (582-2022): 5.83e-14: 80.2: 10.54		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		965409 ARI1B_HUMAN (582-2022): 5.83e-14: 80.2: 10.54		FLI1_HUMAN (1-237): 3.12e-65: 210: 45.23
+	Hs
		507518 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		507468 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Mm
		542772 SMCA4_MOUSE (351-700): 1.27e-23: 112: 16.81		ETS2_MOUSE (10-153): 1.58e-49: 170: 44.83
+	Hs
		542042 ARI1B_HUMAN (582-2022): 5.83e-14: 80.2: 10.54		ETS1_HUMAN (8-151): 2.42e-54: 182: 46.31
+	Hs
		794577 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		ETV4_HUMAN (36-186): 3.64e-46: 161: 39.74
+	Hs
		785430 NCOR2_HUMAN (296-2055): 1.78e-19: 98.3: 8.11		ELK3_HUMAN (61-215): 1.5e-41: 147: 29.68
+	Hs
		794554 ARI1B_HUMAN (582-2022): 5.83e-14: 80.2: 10.54		ETV4_HUMAN (36-186): 3.64e-46: 161: 39.74
+	Hs
		781237 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		ETV3_HUMAN (30-193): 7.5e-48: 166: 39.39
+	Hs
		785417 CHD7_HUMAN (169-662): 2.63e-11: 71.8: 12.93		ELK3_HUMAN (61-215): 1.5e-41: 147: 29.68