HitPredict

Interactor 1: NCOA6 (Q14686)
Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)
Gene: NCOA6

Interactor 2: CXXC1 (Q9P0U4)
CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1)
Gene: CXXC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0035097 - histone methyltransferase complex GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2063 Hs			1 656
+	Hs
		1057802 NCOA6_HUMAN (1-2063): 0: 746: 100.00		KMT2B_HUMAN (75-373): 1.02e-41: 165: 18.96
+	Hs
		975251 NCOA6_HUMAN (1-2063): 0: 746: 100.00		KMT2A_HUMAN (74-341): 2.38e-36: 148: 19.79
+	Hs
		1243846 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		CXXC1_HUMAN (1-656): 0: 739: 100.00
+	Hs
		1243852 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		KMT2B_HUMAN (75-373): 1.02e-41: 165: 18.96
+	Hs
		975285 KMT2C_HUMAN (535-1739): 1.33e-10: 69.2: 11.23		KMT2A_HUMAN (74-341): 2.38e-36: 148: 19.79
+	Dm
		1370354 Q9VLS7_DROME (1052-2062): 6.68e-21: 102: 9.01		NU301_DROME (9-96): 5.22e-14: 78.1: 32.58
+	Hs
		1056908 MDC1_HUMAN (157-945): 1.46e-12: 75.8: 11.15		PHF3_HUMAN (31-82): 3.7e-09: 62.5: 42.11