HitPredict

Interactor 1: PSF1 (Q14691)
DNA replication complex GINS protein PSF1 (GINS complex subunit 1)
Gene: GINS1

Interactor 2: MCM8 (Q9UJA3)
DNA helicase MCM8 (EC 3.6.4.12) (Minichromosome maintenance 8)
Gene: MCM8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32769987
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	MCM~Sld5
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 840
+	Hs
		832463 PSF1_HUMAN (1-196): 2.23e-101: 292: 100.00		MCM2_HUMAN (33-824): 0: 728: 27.95
+	Hs
		708646 PSF1_HUMAN (1-196): 2.23e-101: 292: 100.00		MCM5_HUMAN (66-822): 0: 708: 24.94
+	Hs
		708909 PSF1_HUMAN (1-196): 2.23e-101: 292: 100.00		MCM7_HUMAN (85-813): 0: 656: 25.82
+	Dm
		1366525 Q9W0I7_DROME (1-194): 2.85e-90: 264: 51.53		MCM5_DROME (66-821): 0: 668: 24.37
+	Dm
		1376134 Q9W0I7_DROME (1-194): 2.85e-90: 264: 51.53		MCM3_DROME (92-755): 0: 644: 26.86
+	Ce
		1094509 PSF1_CAEEL (4-192): 5.91e-78: 233: 40.74		MCM5_CAEEL (70-822): 0: 669: 24.37
+	Ce
		1094587 PSF1_CAEEL (4-192): 5.91e-78: 233: 40.74		MCM4_CAEEL (108-835): 0: 656: 26.19
+	Sc
		675576 PSF1_YEAST (1-194): 1.26e-58: 184: 26.54		MCM4_YEAST (64-836): 0: 679: 25.79
+	Sc
		667904 PSF1_YEAST (1-194): 1.26e-58: 184: 26.54		MCM5_YEAST (68-836): 0: 669: 25.24
+	Sc
		744800 PSF1_YEAST (1-194): 1.26e-58: 184: 26.54		MCM7_YEAST (50-820): 0: 668: 26.29
+	Sc
		667656 PSF1_YEAST (1-194): 1.26e-58: 184: 26.54		MCM2_YEAST (59-751): 0: 666: 27.56
+	Ce
		712441 PSF1_CAEEL (4-192): 5.91e-78: 233: 40.74		MCM6_CAEEL (193-749): 2.31e-74: 261: 32.66
+	Sc
		859034 PSF1_YEAST (1-194): 1.26e-58: 184: 26.54		MCM6_YEAST (164-772): 5.07e-82: 286: 31.92