HitPredict

Interactor 1: UBP10 (Q14694)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: USP10

Interactor 2: PP6R1 (Q9UPN7)
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1)
Gene: PPP6R1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 29395067, 33961781, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 798 Hs			1 881
+	Hs
		257177 UBP10_HUMAN (1-798): 0: 720: 100.00		PP6R2_HUMAN (1-880): 0: 793: 40.08
+	Hs
		1058222 UBP10_HUMAN (1-798): 0: 720: 100.00		PP6R3_HUMAN (1-876): 0: 766: 43.85
+	Hs
		1173834 UBP49_HUMAN (362-797): 1.38e-81: 277: 15.45		PP6R1_HUMAN (1-881): 0: 828: 100.00
+	Hs
		1126060 UBP21_HUMAN (200-793): 7.22e-100: 322: 16.69		PP6R3_HUMAN (1-876): 0: 766: 43.85
+	Hs
		1126055 UBP36_HUMAN (369-795): 4.36e-90: 309: 22.94		PP6R3_HUMAN (1-876): 0: 766: 43.85
+	Hs
		257190 UBP49_HUMAN (362-797): 1.38e-81: 277: 15.45		PP6R2_HUMAN (1-880): 0: 793: 40.08
+	Hs
		1125997 UBP49_HUMAN (362-797): 1.38e-81: 277: 15.45		PP6R3_HUMAN (1-876): 0: 766: 43.85