HitPredict

Interactor 1: UBP10 (Q14694)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: USP10

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25861989
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006974 - DNA damage response GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 798 Hs			1 522
+	Hs
		1058285 UBP10_HUMAN (1-798): 0: 720: 100.00		TRAF4_HUMAN (54-500): 6.36e-91: 287: 26.11
+	Hs
		1058275 UBP10_HUMAN (1-798): 0: 720: 100.00		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Hs
		1052655 UBP10_HUMAN (1-798): 0: 720: 100.00		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		271228 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		1356323 UBP21_HUMAN (200-793): 7.22e-100: 322: 16.69		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		1377879 UBP3_HUMAN (394-792): 1.31e-81: 272: 20.86		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		271081 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1020743 U17L2_HUMAN (347-796): 2.97e-81: 271: 25.27		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		271082 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		271032 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		RO52_HUMAN (64-403): 5.77e-45: 166: 14.97
+	Hs
		271027 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		271136 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		TRI50_HUMAN (60-403): 1.01e-39: 152: 14.12
+	Hs
		271189 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		TRIM5_HUMAN (56-315): 8.46e-38: 147: 16.11
+	Mm
		1193545 UBP8_MOUSE (61-793): 1.85e-126: 406: 19.34		RNF41_MOUSE (55-177): 2.68e-17: 84.9: 33.33
+	Hs
		1318717 UBP21_HUMAN (200-793): 7.22e-100: 322: 16.69		TRIM5_HUMAN (56-315): 8.46e-38: 147: 16.11
+	Hs
		777079 UBP8_HUMAN (61-793): 7.74e-115: 376: 18.02		RNF41_HUMAN (55-177): 2.33e-17: 84.9: 33.33
+	Hs
		1019375 UBP36_HUMAN (369-795): 4.36e-90: 309: 22.94		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		271163 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		RN166_HUMAN (61-222): 7.37e-16: 79.1: 22.94
+	Hs
		271142 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		LNX2_HUMAN (58-183): 1.56e-11: 69.1: 21.88
+	Hs
		271168 UBP2_HUMAN (161-793): 7.79e-111: 352: 16.82		RN125_HUMAN (62-193): 1.59e-11: 66: 25.83