HitPredict

Interactor 1: KCNB1 (Q14721)
Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (h-DRK1) (Voltage-gated potassium channel subunit Kv2.1)
Gene: KCNB1

Interactor 2: KCNG2 (Q9UJ96)
Potassium voltage-gated channel subfamily G member 2 (Cardiac potassium channel subunit) (Voltage-gated potassium channel subunit Kv6.2)
Gene: KCNG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	10551266
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	BTB_2~BTB_2, Ion_trans~Ion_trans
Common GO terms	GO:0005251 - delayed rectifier potassium channel activity GO:0005886 - plasma membrane GO:0008076 - voltage-gated potassium channel complex GO:0051260 - protein homooligomerization GO:0071805 - potassium ion transmembrane transport
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 858 Hs			1 466
+	Hs
		1058645 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNB2_HUMAN (3-454): 2.6e-137: 418: 37.67
+	Hs
		1058633 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNB1_HUMAN (2-454): 6.12e-136: 413: 36.26
+	Mm
		61654 KCNB1_MOUSE (1-858): 0: 712: 93.71		KCNB2_MOUSE (3-454): 3.79e-138: 421: 37.89
+	Hs
		1058649 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG1_HUMAN (5-455): 1.04e-114: 348: 56.77
+	Hs
		1058643 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG4_HUMAN (9-454): 1.05e-112: 343: 56.73
+	Hs
		1058647 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNS3_HUMAN (11-417): 5.42e-111: 338: 34.29
+	Hs
		1273152 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNB2_HUMAN (3-454): 2.6e-137: 418: 37.67
+	Hs
		1058642 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNG3_HUMAN (12-421): 5.7e-104: 318: 41.57
+	Hs
		1273157 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNF1_HUMAN (6-454): 5.59e-119: 359: 29.36
+	Hs
		1273162 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG1_HUMAN (5-455): 1.04e-114: 348: 56.77
+	Hs
		1058636 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNV1_HUMAN (21-438): 1.72e-80: 259: 37.82
+	Hs
		1255150 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG4_HUMAN (9-454): 1.05e-112: 343: 56.73
+	Hs
		1273155 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNS3_HUMAN (11-417): 5.42e-111: 338: 34.29
+	Hs
		1058644 KCNB1_HUMAN (1-858): 0: 725: 100.00		KCNV2_HUMAN (21-416): 4.13e-71: 236: 34.79
+	Hs
		1251106 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNG3_HUMAN (12-421): 5.7e-104: 318: 41.57
+	Hs
		1161871 KCNB2_HUMAN (2-858): 0: 640: 60.68		KCNV1_HUMAN (21-438): 1.72e-80: 259: 37.82