HitPredict

Interactor 1: LTBP1 (Q14766)
Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)
Gene: LTBP1

Interactor 2: PCD12 (Q9NPG4)
Protocadherin-12 (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cad-2) (VE-cadherin-2) [Cleaved into: Protocadherin-12, secreted form]
Gene: PCDH12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1721 Hs			1 1184
+	Hs
		1059055 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDG6_HUMAN (2-834): 0: 824: 30.09
+	Hs
		1059056 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDG5_HUMAN (2-918): 0: 818: 27.87
+	Hs
		1059054 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDG7_HUMAN (1-557): 5.39e-125: 409: 24.66
+	Hs
		1059046 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDA4_HUMAN (137-1015): 1.15e-119: 395: 19.41
+	Hs
		1059052 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDGE_HUMAN (3-452): 6.62e-101: 343: 24.35
+	Hs
		1059045 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDGG_HUMAN (3-452): 8.06e-99: 337: 26.30
+	Hs
		1059053 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDG9_HUMAN (247-1095): 3.44e-98: 336: 18.76
+	Hs
		1059047 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDAC_HUMAN (3-269): 1.25e-33: 142: 17.63
+	Hs
		1059050 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDBB_HUMAN (649-959): 6.06e-10: 65.9: 9.09
+	Hs
		1059049 LTBP1_HUMAN (1-1721): 0: 643: 100.00		PCDB6_HUMAN (640-953): 1.75e-09: 64.3: 12.32
+	Hs
		1376963 JAG2_HUMAN (192-812): 2.63e-18: 94.1: 9.43		PCDB3_HUMAN (362-803): 1.42e-50: 194: 20.48