HitPredict

Interactor 1: CBX2 (Q14781)
Chromobox protein homolog 2
Gene: CBX2

Interactor 2: SCML1 (Q9UN30)
Sex comb on midleg-like protein 1
Gene: SCML1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24981860, 22325352
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 532 Hs			1 329
+	Hs
		123342 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		SCML1_HUMAN (1-329): 1.77e-123: 359: 100.00
+	Hs
		1059204 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		SCML2_HUMAN (109-325): 7.08e-47: 170: 31.44
+	Hs
		1059182 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		SCMH1_HUMAN (131-325): 1.54e-46: 168: 30.85
+	Hs
		943062 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		PHC1_HUMAN (189-324): 4.41e-34: 134: 26.47
+	Hs
		1059170 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		PHC2_HUMAN (146-324): 1.16e-33: 133: 19.23
+	Hs
		1059177 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		PHC3_HUMAN (162-324): 7.6e-33: 130: 21.47
+	Hs
		1059207 CBX2_HUMAN (1-532): 6.32e-156: 457: 100.00		LMBL1_HUMAN (156-306): 8.18e-27: 113: 12.65
+	Mm
		675498 CBX2_MOUSE (1-532): 1.26e-145: 430: 81.84		PHC1_MOUSE (189-324): 1.76e-33: 132: 27.21
+	Mm
		675500 CBX2_MOUSE (1-532): 1.26e-145: 430: 81.84		PHC3_MOUSE (162-324): 2.01e-33: 132: 21.47
+	Hs
		123346 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		SCML2_HUMAN (109-325): 7.08e-47: 170: 31.44
+	Hs
		123303 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		SCMH1_HUMAN (131-325): 1.54e-46: 168: 30.85
+	Hs
		316200 CBX6_HUMAN (3-242): 2.28e-36: 141: 30.29		SCML1_HUMAN (1-329): 1.77e-123: 359: 100.00
+	Hs
		123234 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		PHC1_HUMAN (189-324): 4.41e-34: 134: 26.47
+	Hs
		123280 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		PHC2_HUMAN (146-324): 1.16e-33: 133: 19.23
+	Hs
		123290 CBX4_HUMAN (3-522): 6.17e-110: 340: 21.89		PHC3_HUMAN (162-324): 7.6e-33: 130: 21.47
+	Dr
		1193375 Q804D1_DANRE (3-521): 3.29e-99: 310: 24.04		PHC2_DANRE (146-324): 4.31e-38: 145: 24.34
+	Hs
		316124 CBX6_HUMAN (3-242): 2.28e-36: 141: 30.29		SCMH1_HUMAN (131-325): 1.54e-46: 168: 30.85
+	Hs
		316005 CBX6_HUMAN (3-242): 2.28e-36: 141: 30.29		PHC1_HUMAN (189-324): 4.41e-34: 134: 26.47
+	Hs
		316088 CBX6_HUMAN (3-242): 2.28e-36: 141: 30.29		PHC2_HUMAN (146-324): 1.16e-33: 133: 19.23
+	Hs
		316103 CBX6_HUMAN (3-242): 2.28e-36: 141: 30.29		PHC3_HUMAN (162-324): 7.6e-33: 130: 21.47