HitPredict

Interactor 1: CASP8 (Q14790)
Caspase-8 (CASP-8) (EC 3.4.22.61) (Apoptotic cysteine protease) (Apoptotic protease Mch-5) (CAP4) (FADD-homologous ICE/ced-3-like protease) (FADD-like ICE) (FLICE) (ICE-like apoptotic protease 5) (MORT1-associated ced-3 homolog) (MACH) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
Gene: CASP8

Interactor 2: IFT57 (Q9NWB7)
Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2)
Gene: IFT57

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11788820, 17898872
Identification Methods	affinity chromatography technology, classical fluorescence spectroscopy
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006915 - apoptotic process
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 479 Hs			1 429
+	Hs
		1271830 CASPA_HUMAN (1-447): 1.34e-134: 400: 31.76		IFT57_HUMAN (1-429): 0: 698: 100.00
+	Hs
		667492 CASP1_HUMAN (192-478): 1.67e-85: 270: 22.33		IFT57_HUMAN (1-429): 0: 698: 100.00