HitPredict

Interactor 1: GRM7 (Q14831)
Metabotropic glutamate receptor 7 (mGluR7)
Gene: GRM7

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.647

Property	Details
Experiments	11891216, 11007882
Identification Methods	pull down, two hybrid, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 915 Hs			1 415
+	Rn
		723203 GRM7_RAT (1-915): 0: 1002: 99.34		PICK1_RAT (1-415): 0: 597: 96.39
+	Rn
		680331 GRM3_RAT (2-896): 0: 806: 42.24		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		1059611 GRM3_HUMAN (2-896): 0: 803: 43.23		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		680328 GRM2_RAT (28-896): 0: 784: 43.57		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		1022367 GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Rn
		786686 GRIK2_RAT (4-653): 2.58e-105: 349: 14.10		PICK1_RAT (1-415): 0: 597: 96.39
+	Rn
		611607 GRIK1_RAT (12-653): 4.88e-92: 314: 14.49		PICK1_RAT (1-415): 0: 597: 96.39
+	Hs
		761212 GRIK1_HUMAN (12-653): 3.08e-94: 319: 14.78		PICK1_HUMAN (1-415): 0: 592: 100.00