HitPredict

Interactor 1: GRM7 (Q14831)
Metabotropic glutamate receptor 7 (mGluR7)
Gene: GRM7

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11891216
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0045211 - postsynaptic membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 915 Hs			1 1128
+	Rn
		723202 GRM7_RAT (1-915): 0: 1002: 99.34		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		680333 GRM4_RAT (28-915): 0: 916: 70.11		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Hs
		1059612 GRM3_HUMAN (2-896): 0: 803: 43.23		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		1053703 GRM2_HUMAN (28-896): 0: 774: 43.34		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Rn
		680329 GRM3_RAT (2-896): 0: 806: 42.24		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		722955 GRM6_RAT (55-868): 0: 800: 68.09		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Mm
		1143332 GRM7_MOUSE (1-915): 0: 1004: 99.45		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		1022369 GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		761215 GRIK1_HUMAN (12-653): 3.08e-94: 319: 14.78		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Mm
		1143542 GRM3_MOUSE (2-896): 0: 807: 42.35		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Rn
		291492 GRM5_RAT (32-869): 0: 779: 39.86		MAGI2_RAT (3-179): 3.81e-17: 89.4: 20.56
+	Ce
		101944 GRM1_CAEEL (4-888): 0: 698: 36.67		G1K0W3_CAEEL (959-1128): 5.3e-10: 65.9: 14.04
+	Hs
		1021483 GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10		DLG1_HUMAN (9-377): 2.52e-17: 89.7: 13.17
+	Hs
		1022366 GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10		DLG3_HUMAN (803-1120): 7.46e-15: 81.7: 14.15
+	Hs
		942335 GRIK2_HUMAN (4-653): 4.36e-107: 354: 14.10		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Rn
		677766 GRIK2_RAT (4-653): 2.58e-105: 349: 14.10		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		761217 GRIK2_MOUSE (4-653): 2.14e-105: 349: 14.10		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		761199 GRIK1_HUMAN (12-653): 3.08e-94: 319: 14.78		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74