HitPredict

Interactor 1: GRM3 (Q14832)
Metabotropic glutamate receptor 3 (mGluR3)
Gene: GRM3

Interactor 2: GRIP1 (Q9Y3R0)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	11891216
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0045211 - postsynaptic membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 879 Hs			1 1128
+	Rn
		680329 GRM3_RAT (1-879): 0: 935: 96.59		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Hs
		1059609 GRM7_HUMAN (24-876): 0: 828: 43.49		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Hs
		1053703 GRM2_HUMAN (24-879): 0: 816: 67.79		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Rn
		723202 GRM7_RAT (7-876): 0: 827: 42.91		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		680333 GRM4_RAT (15-874): 0: 815: 43.65		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Rn
		722955 GRM6_RAT (27-855): 0: 738: 44.78		GRIP1_RAT (1-1128): 0: 640: 93.88
+	Mm
		1143542 GRM3_MOUSE (1-879): 0: 934: 96.70		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Hs
		761215 GRIK1_HUMAN (19-503): 2.2e-77: 272: 13.12		GRIP1_HUMAN (1-1128): 0: 676: 100.00
+	Mm
		1143332 GRM7_MOUSE (7-876): 0: 827: 42.91		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74
+	Rn
		291492 GRM5_RAT (30-846): 0: 766: 42.26		MAGI2_RAT (3-179): 3.81e-17: 89.4: 20.56
+	Ce
		101944 GRM1_CAEEL (24-877): 0: 702: 39.08		G1K0W3_CAEEL (959-1128): 5.3e-10: 65.9: 14.04
+	Hs
		761199 GRIK1_HUMAN (19-503): 2.2e-77: 272: 13.12		DLG4_HUMAN (999-1126): 8.04e-15: 81.3: 20.74
+	Rn
		677766 GRIK2_RAT (1-501): 3.15e-77: 271: 13.26		DLG4_RAT (999-1126): 7.26e-15: 81.7: 20.74
+	Mm
		761217 GRIK2_MOUSE (1-501): 6.22e-75: 265: 14.59		DLG4_MOUSE (999-1126): 8.76e-15: 81.3: 20.74