HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	32744500, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1912 Hs			1 726
+	Hs
		631426 CHD4_HUMAN (1-1912): 0: 1719: 100.00		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		631414 CHD3_HUMAN (23-1905): 0: 1595: 66.89		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		1059940 CHD4_HUMAN (1-1912): 0: 1719: 100.00		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		998717 CHD4_HUMAN (1-1912): 0: 1719: 100.00		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Mm
		70929 CHD4_MOUSE (1-1900): 0: 1680: 97.80		EP300_MOUSE (4-177): 2.63e-34: 143: 22.86
+	Hs
		244447 CHD4_HUMAN (1-1912): 0: 1719: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		1059760 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PHIP_HUMAN (5-708): 5.37e-19: 94.5: 10.37
+	Hs
		1059704 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		1018748 CHD3_HUMAN (23-1905): 0: 1595: 66.89		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		1255051 CHD5_HUMAN (86-1909): 0: 1584: 71.18		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		998619 CHD3_HUMAN (23-1905): 0: 1595: 66.89		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		244356 CHD3_HUMAN (23-1905): 0: 1595: 66.89		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		1018557 CHD3_HUMAN (23-1905): 0: 1595: 66.89		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		600135 CHD3_HUMAN (23-1905): 0: 1595: 66.89		TAF1_HUMAN (23-303): 3.47e-17: 88.7: 13.52
+	Hs
		1255033 CHD5_HUMAN (86-1909): 0: 1584: 71.18		PHIP_HUMAN (5-708): 5.37e-19: 94.5: 10.37
+	Dm
		332801 CHDM_DROME (1-1904): 0: 1364: 50.85		Q8SX63_DROME (264-726): 1.49e-10: 67.1: 14.13
+	Hs
		1199209 CHD7_HUMAN (3-1678): 0: 805: 23.02		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Mm
		102332 SMCA1_MOUSE (557-1597): 0: 798: 27.05		G3UWZ0_MOUSE (46-157): 1.31e-20: 99.6: 28.21
+	Mm
		102334 SMCA5_MOUSE (601-1624): 0: 795: 26.39		G3UWZ0_MOUSE (46-157): 1.31e-20: 99.6: 28.21
+	Mm
		291490 SMCA5_MOUSE (601-1624): 0: 795: 26.39		BAZ1A_MOUSE (46-157): 1.14e-20: 99.6: 28.21