Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 28977666, 10545197, 9804427, 24981860, 32744500, 25593309, 33283408, 11003653, 9790534, 9885572, 21670149, 12493763, 30737378, 35271311, 21258344, 23752268, 26949739
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 12 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1912
Hs

1 488
+ Mm
+ Hs
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+ Mm
+ Hs
+ Hs
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+ Dm
+ Ce
+ Ce
+ Hs
+ Dm
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+ Sp
+ Sp
+ Mm
+ Mm

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Last updated: 15 Jul 2024