HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: DDX50 (Q9BQ39)
ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)
Gene: DDX50

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28977666, 32744500
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEAD~Helicase_C, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0016020 - membrane GO:0016887 - ATP hydrolysis activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 737
+	Hs
		1059892 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX21_HUMAN (20-736): 5.59e-143: 439: 59.86
+	Hs
		1059774 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX17_HUMAN (74-587): 1.25e-136: 421: 24.66
+	Hs
		571456 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX5_HUMAN (73-588): 1.42e-137: 420: 25.58
+	Hs
		1059712 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX42_HUMAN (8-732): 1.01e-127: 404: 20.18
+	Hs
		134046 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX3X_HUMAN (15-526): 5.63e-129: 399: 24.86
+	Hs
		1018663 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX50_HUMAN (1-737): 1.3e-174: 519: 100.00
+	Hs
		1018702 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX21_HUMAN (20-736): 5.59e-143: 439: 59.86
+	Hs
		1018621 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX17_HUMAN (74-587): 1.25e-136: 421: 24.66
+	Hs
		571420 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX5_HUMAN (73-588): 1.42e-137: 420: 25.58
+	Hs
		1018563 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX42_HUMAN (8-732): 1.01e-127: 404: 20.18
+	Hs
		134003 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX3X_HUMAN (15-526): 5.63e-129: 399: 24.86