HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: DDX24 (Q9GZR7)
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)
Gene: DDX24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28977666, 32744500
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEAD~Helicase_C, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0016020 - membrane GO:0016887 - ATP hydrolysis activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 859
+	Hs
		134046 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		571456 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Hs
		1018685 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		134003 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		571420 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Hs
		1059902 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		1059931 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1059712 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX42_HUMAN (4-267): 1.44e-16: 86.7: 14.61
+	Hs
		1059863 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX47_HUMAN (177-261): 2.92e-12: 71.7: 36.47
+	Hs
		1059774 CHD4_HUMAN (1-1912): 0: 1719: 100.00		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Hs
		1018712 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		1018741 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		1018563 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX42_HUMAN (4-267): 1.44e-16: 86.7: 14.61
+	Hs
		1018690 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX47_HUMAN (177-261): 2.92e-12: 71.7: 36.47
+	Hs
		1018621 CHD3_HUMAN (23-1905): 0: 1595: 66.89		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Hs
		229507 SMCA5_HUMAN (578-1624): 0: 791: 26.01		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69