HitPredict

Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1912 Hs			1 559
+	Hs
		1054315 CHD4_HUMAN (1-1912): 0: 1719: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1018737 CHD3_HUMAN (23-1905): 0: 1595: 66.89		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		1018476 CHD3_HUMAN (23-1905): 0: 1595: 66.89		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1031332 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516522 CHD4_HUMAN (1-1912): 0: 1719: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1018458 CHD3_HUMAN (23-1905): 0: 1595: 66.89		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516483 CHD3_HUMAN (23-1905): 0: 1595: 66.89		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		229395 SMCA5_HUMAN (578-1624): 0: 791: 26.01		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1020333 CHD8_HUMAN (489-1678): 0: 752: 28.31		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		642799 CHD8_HUMAN (489-1678): 0: 752: 28.31		ELAV4_HUMAN (16-210): 6.97e-20: 93.7: 16.92
+	Hs
		516702 CHD8_HUMAN (489-1678): 0: 752: 28.31		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64