HitPredict

Interactor 1: STAR3 (Q14849)
StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3)
Gene: STARD3

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	33124732, 24105263
Identification Methods	x-ray crystallography, affinity chromatography technology, pull down, cross-linking study
Interaction Type	association, physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0030301 - cholesterol transport GO:0042803 - protein homodimerization activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 249
+	Hs
		310636 STAR3_HUMAN (1-445): 2.22e-162: 466: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1060098 STAR3_HUMAN (1-445): 2.22e-162: 466: 100.00		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Hs
		321360 STR3N_HUMAN (1-211): 1.03e-96: 291: 59.16		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1349644 PPCT_HUMAN (240-444): 1.99e-53: 179: 12.44		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		321342 STR3N_HUMAN (1-211): 1.03e-96: 291: 59.16		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Hs
		87515 C9JPX5_HUMAN (1-205): 1.05e-94: 285: 57.97		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Hs
		1245691 CERT_HUMAN (176-440): 9.92e-43: 161: 12.03		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34