HitPredict

Interactor 1: MYPC3 (Q14896)
Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)
Gene: MYBPC3

Interactor 2: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.50	0.462

Property	Details
Experiments	21569246
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1274 Hs			1 2346
+	Hs
		1053311 MYPC2_HUMAN (6-772): 6.84e-40: 163: 13.37		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		522615 MYPC3_HUMAN (1-1274): 0: 747: 100.00		MYH7_HUMAN (1-709): 1.93e-23: 111: 10.58
+	Mm
		250933 MYPC3_MOUSE (1-1274): 0: 727: 87.52		MYH6_MOUSE (1379-2333): 4.13e-28: 127: 9.32
+	Hs
		234531 DSCAM_HUMAN (970-1273): 1.84e-22: 107: 18.04		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Mm
		250923 MYPC3_MOUSE (1-1274): 0: 727: 87.52		LAMB1_MOUSE (342-655): 3.81e-12: 74.3: 23.55
+	Hs
		852390 MYOM1_HUMAN (769-863): 1.82e-10: 67.8: 38.14		MYOME_HUMAN (1-2346): 0: 703: 100.00
+	Hs
		1018317 CNTN1_HUMAN (453-1274): 4.51e-54: 208: 14.40		MYH4_HUMAN (1279-2334): 2.89e-32: 140: 9.95
+	Hs
		528411 MYPC2_HUMAN (6-772): 6.84e-40: 163: 13.37		MYH8_HUMAN (1820-2316): 2.84e-12: 75: 11.75
+	Hs
		255785 OBSL1_HUMAN (15-95): 7.76e-12: 72.6: 34.57		GOGB1_HUMAN (880-2332): 2.13e-37: 157: 10.38
+	Hs
		522597 MYOM2_HUMAN (771-1164): 8.65e-18: 91.7: 24.94		MYH7_HUMAN (1-709): 1.93e-23: 111: 10.58
+	Dm
		404245 TITIN_DROME (1109-1273): 4.41e-15: 83.4: 24.10		MYSA_DROME (29-785): 1.4e-23: 112: 11.88
+	Hs
		255591 OBSL1_HUMAN (15-95): 7.76e-12: 72.6: 34.57		CENPF_HUMAN (1261-2312): 1.38e-21: 105: 10.69
+	Hs
		255442 OBSL1_HUMAN (15-95): 7.76e-12: 72.6: 34.57		LAMB1_HUMAN (342-655): 2.89e-12: 74.7: 24.86
+	Hs
		255483 OBSL1_HUMAN (15-95): 7.76e-12: 72.6: 34.57		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72
+	Hs
		551790 TITIN_HUMAN (785-1011): 8.33e-11: 69.1: 10.29		DESP_HUMAN (6-681): 6.09e-10: 67.4: 20.72