HitPredict

Interactor 1: NC2A (Q14919)
Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha)
Gene: DRAP1

Interactor 2: NC2A (Q14919)
Dr1-associated corepressor (Dr1-associated protein 1) (Negative cofactor 2-alpha) (NC2-alpha)
Gene: DRAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.826

The method score is based on:

Property	Details
Experiments	25416956, 27107012
Identification Methods	two hybrid, two hybrid array, barcode fusion genetics two hybrid, validated two hybrid
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CBFD_NFYB_HMF~CBFD_NFYB_HMF
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001046 - core promoter sequence-specific DNA binding GO:0001091 - RNA polymerase II general transcription initiation factor binding GO:0005634 - nucleus GO:0006366 - transcription by RNA polymerase II and 5 others more... GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0017025 - TBP-class protein binding GO:0017054 - negative cofactor 2 complex GO:0046982 - protein heterodimerization activity GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	205
Hs

1	205

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024