HitPredict

Interactor 1: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Interactor 2: SMRD2 (Q92925)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B) (BAF60B)
Gene: SMARCD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 502 Hs			1 531
+	Hs
		1060352 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		SMRD1_HUMAN (50-531): 0: 600: 65.11
+	Hs
		1060312 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		SMRD3_HUMAN (70-531): 0: 581: 69.70
+	Hs
		1018250 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		SMRD2_HUMAN (1-531): 0: 640: 100.00
+	Hs
		443227 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		SMRD2_HUMAN (1-531): 0: 640: 100.00
+	Hs
		1018254 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		SMRD1_HUMAN (50-531): 0: 600: 65.11
+	Hs
		135145 NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69		SMRD2_HUMAN (1-531): 0: 640: 100.00
+	Hs
		443231 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		SMRD1_HUMAN (50-531): 0: 600: 65.11
+	Hs
		135147 NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69		SMRD1_HUMAN (50-531): 0: 600: 65.11
+	Ce
		137207 RPB1_CAEEL (229-496): 1.4e-10: 66.2: 13.98		SWIC2_CAEEL (77-529): 3.95e-170: 490: 46.55
+	Hs
		152648 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		KMT2D_HUMAN (7-159): 3.54e-17: 87.6: 23.60
+	Hs
		152636 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		KMT2D_HUMAN (7-159): 3.54e-17: 87.6: 23.60
+	Hs
		152576 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		KMT2D_HUMAN (7-159): 3.54e-17: 87.6: 23.60
+	Hs
		135048 NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69		KMT2D_HUMAN (7-159): 3.54e-17: 87.6: 23.60
+	Hs
		297843 SC31A_HUMAN (196-498): 3.9e-11: 67.7: 9.78		SC24D_HUMAN (1-148): 2.45e-31: 131: 24.86
+	Hs
		123781 SPT5H_HUMAN (144-357): 1.74e-12: 71.9: 13.60		KMT2D_HUMAN (7-159): 3.54e-17: 87.6: 23.60
+	Hs
		152667 KMT2C_HUMAN (197-498): 9.61e-09: 60.4: 9.61		KMT2D_HUMAN (7-159): 3.54e-17: 87.6: 23.60
+	Mm
		1351630 PCLO_MOUSE (215-500): 3.08e-12: 71.6: 13.54		PCLO_MOUSE (3-152): 6.49e-11: 67.6: 14.19