HitPredict

Interactor 1: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29844126, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 502 Hs			1 2517
+	Hs
		1018255 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		443234 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		818059 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		727871 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Hs
		727745 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Hs
		1060360 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		MINT_HUMAN (730-2515): 3e-28: 127: 9.45
+	Hs
		818805 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		SOX9_HUMAN (1031-1201): 1.04e-24: 112: 23.08
+	Hs
		817985 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		443149 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		1060396 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		1060330 NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00		KMT2C_HUMAN (1873-2516): 1.5e-09: 66.4: 10.57
+	Hs
		727855 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Hs
		443140 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Hs
		727735 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Hs
		443139 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Hs
		818795 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		SOX9_HUMAN (1031-1201): 1.04e-24: 112: 23.08
+	Hs
		443150 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		SOX9_HUMAN (1031-1201): 1.04e-24: 112: 23.08
+	Hs
		443188 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30
+	Hs
		1018287 NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Hs
		443276 NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06