HitPredict

Interactor 1: KI3S1 (Q14943)
Killer cell immunoglobulin-like receptor 3DS1 (Natural killer-associated transcript 10) (NKAT-10)
Gene: KIR3DS1

Interactor 2: Q95J06 (Q95J06)
HLA class I histocompatibility antigen A alpha chain (MHC class I antigen) (MHC class I protein) (MHC leukocyte antigen) (Major histocompatibility complex, class I, A)
Gene: HLA-A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27649529
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~ig, MHC_I~ig
Common GO terms	GO:0006955 - immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 382 Hs			1 365
+	Hs
		382420 KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		1060403 KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00		Q5SUL5_HUMAN (1-365): 4.23e-173: 487: 91.78
+	Hs
		382341 KI3L2_HUMAN (1-368): 6.34e-90: 279: 84.51		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		798244 KI3L2_HUMAN (1-368): 6.34e-90: 279: 84.51		Q5S3G3_HUMAN (1-365): 4.46e-175: 492: 92.06
+	Hs
		1060402 KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00		Q546I9_HUMAN (1-362): 1.64e-158: 450: 82.60
+	Hs
		354449 KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		47499 A0A8I5QEB2_HUMAN (1-368): 2.83e-83: 261: 70.65		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		488221 KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00		HLAC_HUMAN (1-364): 5.42e-149: 426: 78.63
+	Hs
		354352 KI3L1_HUMAN (1-368): 2.95e-93: 288: 95.92		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		354353 KI3L2_HUMAN (1-368): 6.34e-90: 279: 84.51		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		673954 KI3S1_HUMAN (1-382): 3.98e-106: 319: 100.00		HLAF_HUMAN (4-348): 2.53e-139: 401: 80.87
+	Hs
		570311 KI3L1_HUMAN (1-368): 2.95e-93: 288: 95.92		HLAG_HUMAN (1-338): 6.03e-148: 422: 81.95
+	Hs
		382280 FGFR1_HUMAN (3-369): 3.89e-60: 209: 14.18		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		47498 A0A8I5QEB2_HUMAN (1-368): 2.83e-83: 261: 70.65		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81
+	Hs
		382306 FGFR2_HUMAN (2-379): 8.05e-60: 208: 13.78		HLAA_HUMAN (1-365): 2.79e-175: 493: 92.33
+	Hs
		673944 KI3L1_HUMAN (1-368): 2.95e-93: 288: 95.92		HLAF_HUMAN (4-348): 2.53e-139: 401: 80.87
+	Hs
		488296 KI3L3_HUMAN (1-368): 9.34e-84: 262: 70.92		HLAC_HUMAN (1-364): 5.42e-149: 426: 78.63
+	Hs
		47500 A0A8I5QEB2_HUMAN (1-368): 2.83e-83: 261: 70.65		HLAC_HUMAN (1-364): 5.42e-149: 426: 78.63
+	Hs
		673945 KI3L2_HUMAN (1-368): 6.34e-90: 279: 84.51		HLAF_HUMAN (4-348): 2.53e-139: 401: 80.87
+	Hs
		354513 LIRB1_HUMAN (21-344): 4.61e-57: 198: 35.53		HLAB_HUMAN (1-362): 7.73e-155: 441: 84.81