HitPredict

Interactor 1: IMB1 (Q14974)
Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)
Gene: KPNB1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30737378, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0019899 - enzyme binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 876 Hs			1 488
+	Hs
		1038385 IMB1_HUMAN (1-876): 0: 635: 100.00		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177156 SF3B1_HUMAN (146-866): 1.96e-78: 279: 12.23		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		1270353 TNPO1_HUMAN (125-870): 3.59e-28: 123: 12.21		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		127332 IPO5_HUMAN (89-863): 6.82e-13: 75: 10.97		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		127260 IPO5_HUMAN (89-863): 6.82e-13: 75: 10.97		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		312410 IPO7_HUMAN (3-848): 8.3e-82: 286: 12.03		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04