HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 726
+	Hs
		631429 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		1061132 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		BRDT_HUMAN (18-695): 2.15e-107: 350: 49.71
+	Hs
		998721 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		876692 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		BRPF1_HUMAN (20-274): 6.8e-26: 116: 14.94
+	Hs
		244452 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		1061186 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		PHIP_HUMAN (5-708): 5.37e-19: 94.5: 10.37
+	Hs
		1061156 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		631458 CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		1123369 CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75		BRDT_HUMAN (18-695): 2.15e-107: 350: 49.71
+	Hs
		1271492 CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08		KAT2B_HUMAN (267-414): 8.8e-32: 134: 25.50
+	Hs
		724792 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		725147 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		998727 EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		244551 CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244025 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244026 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244466 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		243855 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		518903 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		PHIP_HUMAN (5-708): 5.37e-19: 94.5: 10.37