HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 520
+	Hs
		318809 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		K2C75_HUMAN (2-516): 7.92e-95: 300: 48.22
+	Hs
		1061108 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		K2C72_HUMAN (1-502): 4.44e-85: 274: 47.85
+	Hs
		580132 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		K2C4_HUMAN (6-443): 3.19e-73: 243: 55.10
+	Hs
		408987 MYH1_HUMAN (1-831): 3.6e-35: 150: 12.27		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		409080 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		444536 GOGA4_HUMAN (5-528): 2.18e-12: 75: 11.24		K2C7_HUMAN (12-435): 4.77e-122: 367: 53.30
+	Hs
		821662 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		K2C6C_HUMAN (76-448): 1.24e-79: 261: 59.52
+	Hs
		1068595 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		K2C78_HUMAN (1-520): 1.25e-79: 259: 100.00