HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26949739
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2115 Hs			1 488
+	Hs
		1038680 CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		724945 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		725212 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		522611 MYH7_HUMAN (947-2023): 1.11e-36: 155: 11.21		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		522547 MYH1_HUMAN (1-831): 3.6e-35: 150: 12.27		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		528410 MYH8_HUMAN (1122-2115): 6.23e-35: 149: 10.31		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038449 CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038853 MYH4_HUMAN (1-831): 9.18e-34: 145: 12.50		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		724813 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038808 MYH2_HUMAN (1-869): 2.82e-33: 143: 12.06		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038397 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1038380 GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		518865 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		1137105 CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75		HDAC8_HUMAN (33-372): 1.01e-137: 403: 43.40
+	Hs
		725053 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Mm
		1143175 MYH10_MOUSE (5-834): 3.93e-31: 136: 11.65		HDAC6_MOUSE (11-367): 2.93e-104: 338: 24.12
+	Hs
		725261 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1068690 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		728525 MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04
+	Hs
		1059289 GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49		HDAC6_HUMAN (11-363): 6.94e-102: 332: 24.04