HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2115 Hs			1 126
+	Hs
		1061124 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		1061220 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2B1M_HUMAN (1-126): 3.95e-55: 169: 96.03
+	Hs
		241530 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		707636 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918372 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		886111 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		1061168 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03
+	Hs
		241506 CENPE_HUMAN (694-2076): 2.24e-41: 170: 9.63		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		918300 CENPE_HUMAN (694-2076): 2.24e-41: 170: 9.63		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1137101 CROCC_HUMAN (1-1268): 5.14e-34: 146: 13.75		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		724951 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		241463 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		724751 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1274476 MYH2_HUMAN (1-869): 2.82e-33: 143: 12.06		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		724734 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		725214 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		241464 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		725133 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		725122 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		725231 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		H2B1L_HUMAN (1-126): 2.43e-53: 165: 97.62