HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: SMRCD (Q9H4L7)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (EC 3.6.4.12) (ATP-dependent helicase 1) (hHEL1)
Gene: SMARCAD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	30021884, 21549307
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 1026
+	Hs
		846972 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		SMCA4_HUMAN (96-1024): 0: 693: 26.54
+	Hs
		1018486 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		229401 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		SMCA5_HUMAN (353-1021): 0: 594: 29.60
+	Hs
		658673 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		SMCA1_HUMAN (379-1021): 0: 590: 29.56
+	Hs
		1061268 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		HELLS_HUMAN (479-999): 1.2e-93: 318: 37.59
+	Hs
		724799 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		725150 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		CHD3_HUMAN (338-1022): 0: 621: 27.64
+	Hs
		658678 EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15		SMCA1_HUMAN (379-1021): 0: 590: 29.56
+	Hs
		518858 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		ERCC6_HUMAN (21-1021): 0: 595: 20.53