HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: WRP73 (Q9P2S5)
WD repeat-containing protein WRAP73 (WD repeat-containing protein 8) (WD repeat-containing protein antisense to TP73 gene)
Gene: WRAP73

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26545777
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0072686 - mitotic spindle
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 460
+	Hs
		1061204 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		SNR40_HUMAN (170-459): 4.37e-59: 199: 11.07
+	Hs
		1061226 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		KTNB1_HUMAN (8-171): 3.12e-13: 73.7: 18.08
+	Hs
		728524 MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41		WRP73_HUMAN (1-460): 4.09e-100: 308: 100.00
+	Hs
		1192532 CNTRL_HUMAN (3-811): 1.27e-16: 89.3: 11.29		WRP73_HUMAN (1-460): 4.09e-100: 308: 100.00
+	Hs
		197084 CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08		PRP4_HUMAN (50-360): 9.05e-22: 99: 13.75
+	Hs
		792973 CENPE_HUMAN (694-2076): 2.24e-41: 170: 9.63		LIS1_HUMAN (275-459): 3.43e-39: 147: 9.73
+	Hs
		903240 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Mm
		925837 Q155P7_MOUSE (562-1890): 5.59e-30: 133: 11.42		LIS1_MOUSE (275-459): 2.77e-39: 148: 9.73
+	Hs
		903233 GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		518846 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		WDR5_HUMAN (270-456): 8.41e-45: 161: 16.04
+	Hs
		728492 MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41		POC1A_HUMAN (1-76): 5.81e-12: 69: 15.39