HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: TBK1 (Q9UHD2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29251827
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2115 Hs			1 729
+	Hs
		625440 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		1047932 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		KCC1A_HUMAN (7-297): 6.14e-86: 277: 25.09
+	Hs
		724823 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		1313528 CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08		SIK2_HUMAN (9-719): 1.2e-110: 359: 15.54
+	Hs
		725161 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		IKKE_HUMAN (1-716): 4.07e-146: 445: 48.33
+	Hs
		158414 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		IKKB_HUMAN (9-727): 1.01e-139: 430: 18.98
+	Hs
		167486 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		167487 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		IKKA_HUMAN (9-637): 4.09e-121: 381: 21.08
+	Hs
		528401 MYH8_HUMAN (1122-2115): 6.23e-35: 149: 10.31		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		522604 MYH7_HUMAN (947-2023): 1.11e-36: 155: 11.21		CDK3_HUMAN (6-309): 7.85e-116: 352: 20.20
+	Hs
		625176 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		725010 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		SIK2_HUMAN (9-719): 1.2e-110: 359: 15.54
+	Hs
		625177 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		522542 MYH1_HUMAN (1-831): 3.6e-35: 150: 12.27		CDK3_HUMAN (6-309): 7.85e-116: 352: 20.20
+	Hs
		528405 MYH8_HUMAN (1122-2115): 6.23e-35: 149: 10.31		CDK3_HUMAN (6-309): 7.85e-116: 352: 20.20
+	Hs
		625446 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		CDK2_HUMAN (6-312): 1.71e-119: 361: 20.97
+	Hs
		725242 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		SIK2_HUMAN (9-719): 1.2e-110: 359: 15.54
+	Hs
		960128 MYH2_HUMAN (1-869): 2.82e-33: 143: 12.06		CDK3_HUMAN (6-309): 7.85e-116: 352: 20.20
+	Hs
		724967 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		MARK4_HUMAN (9-344): 1.37e-86: 290: 24.48
+	Hs
		725223 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		MARK4_HUMAN (9-344): 1.37e-86: 290: 24.48