HitPredict

Interactor 1: CUL7 (Q14999)
Cullin-7 (CUL-7)
Gene: CUL7

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24711643, 31343991
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1698 Hs			1 4684
+	Hs
		521544 CUL7_HUMAN (1-1698): 0: 2861: 100.00		ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94
+	Hs
		885250 CUL7_HUMAN (1-1698): 0: 2861: 100.00		EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75
+	Hs
		1061633 CUL7_HUMAN (1-1698): 0: 2861: 100.00		SPTN5_HUMAN (690-2798): 1.75e-36: 156: 14.67
+	Hs
		1059213 CUL7_HUMAN (1-1698): 0: 2861: 100.00		GOGB1_HUMAN (2666-3718): 4.33e-13: 78.9: 11.65
+	Hs
		1061690 CUL7_HUMAN (1-1698): 0: 2861: 100.00		MACF1_HUMAN (3704-4616): 3.72e-10: 69.3: 14.92
+	Hs
		551707 CUL7_HUMAN (1-1698): 0: 2861: 100.00		DESP_HUMAN (351-874): 8.53e-10: 68.1: 8.21
+	Hs
		319843 HERC2_HUMAN (838-982): 1.36e-38: 161: 36.55		PLEC_HUMAN (1-4684): 0: 1783: 100.00
+	Mm
		1118139 HERC2_MOUSE (838-982): 5.36e-38: 159: 34.48		SPTB2_MOUSE (1531-3013): 1.72e-17: 93.1: 9.54
+	Mm
		1118168 HERC2_MOUSE (838-982): 5.36e-38: 159: 34.48		MACF1_MOUSE (4303-4628): 3.44e-09: 66.2: 16.56
+	Mm
		1118160 HERC2_MOUSE (838-982): 5.36e-38: 159: 34.48		DYST_MOUSE (4325-4624): 7.75e-09: 65: 17.00