HitPredict

Interactor 1: SHPRH (Q149N8)
E3 ubiquitin-protein ligase SHPRH (EC 2.3.2.27) (EC 3.6.4.-) (RING-type E3 ubiquitin transferase SHPRH) (SNF2, histone-linker, PHD and RING finger domain-containing helicase)
Gene: SHPRH

Interactor 2: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1683 Hs			1 425
+	Hs
		997730 SHPRH_HUMAN (1-1683): 0: 1247: 100.00		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		1083322 CHD5_HUMAN (1253-1682): 1.55e-104: 373: 17.96		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		229413 SMCA5_HUMAN (1267-1682): 2.48e-107: 370: 15.44		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1018507 CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1059641 CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70		RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00
+	Hs
		1018714 CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87		NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15
+	Hs
		997824 CHD5_HUMAN (1253-1682): 1.55e-104: 373: 17.96		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		229377 SMCA5_HUMAN (1267-1682): 2.48e-107: 370: 15.44		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		997695 CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Ce
		954000 CHD3_CAEEL (1155-1682): 1e-99: 358: 13.42		LIN53_CAEEL (1-209): 6.74e-42: 154: 14.16
+	Ce
		104626 LE418_CAEEL (1276-1682): 1.32e-98: 354: 16.75		LIN53_CAEEL (1-209): 6.74e-42: 154: 14.16
+	Dm
		332768 CHDM_DROME (1255-1682): 1.2e-97: 352: 15.95		CAF1_DROME (1-209): 8.04e-42: 154: 13.16
+	Hs
		997936 CHD7_HUMAN (1187-1679): 3.9e-96: 348: 13.11		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		846946 SMCA4_HUMAN (1246-1682): 3.38e-96: 346: 13.91		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		997726 CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70		RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72
+	Hs
		929424 CHD3_HUMAN (1279-1682): 6.88e-103: 368: 17.87		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		929464 CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70		RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41
+	Hs
		903234 CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		903535 CHD8_HUMAN (1145-1679): 9.94e-95: 343: 13.11		WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61
+	Hs
		1059830 CHD4_HUMAN (1275-1682): 1.8e-95: 345: 17.70		GRWD1_HUMAN (307-404): 4.14e-14: 75.7: 23.47