Interactor 1: AT7L3 (Q14CW9)
Ataxin-7-like protein 3 (SAGA-associated factor 11 homolog)
Gene: ATXN7L3

Interactor 2: UBP22 (Q9UPT9)
Ubiquitin carboxyl-terminal hydrolase 22 (EC 3.4.19.12) (Deubiquitinating enzyme 22) (Ubiquitin thioesterase 22) (Ubiquitin-specific-processing protease 22)
Gene: USP22

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 26186194, 28514442, 27601583, 19114550, 32296183, 33961781, 18206972, 37682711, 24981860, 35271311, 19615732, 23382074, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid array, anti tag coimmunoprecipitation, two hybrid prey pooling approach, validated two hybrid, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sgf11~UCH
Common GO terms GO:0000124 - SAGA complex
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006282 - regulation of DNA repair
GO:0006357 - regulation of transcription by RNA polymerase II
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 347
Hs

1 525
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024