Interactor 1: EMC2 (Q15006)
ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)
Gene: EMC2

Interactor 2: EMC5 (Q8N4V1)
ER membrane protein complex subunit 5 (Membrane magnesium transporter 1) (Transmembrane protein 32)
Gene: MMGT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.90 0.921

The method score is based on:

Property Details
Experiments 22119785, 26186194, 26496610, 28514442, 27342126, 33961781, 35271311, 32439656
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MMgT~TPR_19
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
GO:0072546 - EMC complex
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024