HitPredict

Interactor 1: EMC2 (Q15006)
ER membrane protein complex subunit 2 (Tetratricopeptide repeat protein 35) (TPR repeat protein 35)
Gene: EMC2

Interactor 2: ESYT1 (Q9BSJ8)
Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein)
Gene: ESYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	27342126, 37931956, 35271311
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 297 Hs			1 1104
+	Hs
		48356 EMC2_HUMAN (1-297): 1.09e-73: 229: 100.00		ESYT2_HUMAN (848-1101): 9e-14: 78.1: 12.32
+	Hs
		128846 CDC16_HUMAN (55-250): 8.77e-22: 97.2: 15.31		P3C2A_HUMAN (973-1095): 9.86e-10: 65.1: 35.48