Interactor 1: HERP1 (Q15011)
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (Methyl methanesulfonate (MMF)-inducible fragment protein 1)
Gene: HERPUD1
Interactor 2: SYVN1 (Q86TM6)
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)
Gene: SYVN1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.966 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16289116, 21149444, 26424800, 28827405, 31056421, 32738194, 32614325, 23867461 |
| Identification Methods | affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ubiquitin~zf-RING_2 |
| Common GO terms | GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016020 - membrane GO:0030970 - retrograde protein transport, ER to cytosol and 3 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
