Interactor 1: LIN35 (G5EDT1)
Retinoblastoma-like protein homolog lin-35 (Abnormal cell lineage protein 35) (Synthetic multivulva protein lin-35)
Gene: lin-35

Interactor 2: G5EF11 (G5EF11)
E2F/DP family winged-helix DNA-binding domain-containing protein (EFL-1)
Gene: efl-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 16020796, 11463372
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0035189 - Rb-E2F complex
GO:0040027 - negative regulation of vulval development
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 961
Ce

1 342
+ At
+ At
+ At
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Rn
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024