HitPredict

Interactor 1: SEPT2 (Q15019)
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)
Gene: SEPTIN2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007283 - spermatogenesis and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 2527
+	Hs
		91434 E7EPK1_HUMAN (9-357): 3.69e-171: 485: 53.32		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130391 SEPT8_HUMAN (3-348): 2.74e-162: 464: 39.54		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130699 SEPT9_HUMAN (2-320): 2.97e-159: 460: 45.68		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		90114 D6RER5_HUMAN (8-348): 1.64e-161: 460: 39.83		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		945773 SEPT7_HUMAN (11-357): 2.78e-171: 485: 53.61		M3K9_HUMAN (1874-2136): 3.07e-24: 114: 32.38