HitPredict

Interactor 1: SEPT2 (Q15019)
Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)
Gene: SEPTIN2

Interactor 2: BORG4 (Q9H3Q1)
Cdc42 effector protein 4 (Binder of Rho GTPases 4)
Gene: CDC42EP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton GO:0015630 - microtubule cytoskeleton
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 361 Hs			1 356
+	Hs
		198202 SEPT4_HUMAN (17-345): 7.51e-178: 504: 60.34		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1305898 SEPT5_HUMAN (2-346): 3.78e-175: 492: 58.45		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1080980 SEPT7_HUMAN (11-357): 2.78e-171: 485: 53.61		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1267802 SEPT8_HUMAN (3-348): 2.74e-162: 464: 39.54		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1330298 SEPT9_HUMAN (2-320): 2.97e-159: 460: 45.68		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1330293 SEP11_HUMAN (8-348): 3.99e-161: 459: 39.83		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1049012 SEPT6_HUMAN (14-348): 5.19e-160: 457: 40.24		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1330295 SEP10_HUMAN (14-357): 7.49e-159: 454: 38.00		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1330297 SEPT3_HUMAN (6-308): 3.1e-155: 442: 47.71		BORG4_HUMAN (1-356): 3.59e-128: 373: 100.00
+	Hs
		1080995 SEPT7_HUMAN (11-357): 2.78e-171: 485: 53.61		BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21
+	Hs
		150127 SEPT7_HUMAN (11-357): 2.78e-171: 485: 53.61		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86
+	Hs
		1049020 SEPT6_HUMAN (14-348): 5.19e-160: 457: 40.24		BORG2_HUMAN (2-229): 1.35e-56: 186: 24.21
+	Hs
		960668 SEP10_HUMAN (14-357): 7.49e-159: 454: 38.00		BORG5_HUMAN (3-227): 4.09e-53: 181: 32.16
+	Hs
		150125 SEPT6_HUMAN (14-348): 5.19e-160: 457: 40.24		BORG1_HUMAN (1-228): 1.31e-47: 162: 25.86